An Israeli company, CoreBone has come up with a major breakthrough in bone replacement, used for grafts and implants.
“Bone grafts ideally should have four features,” CoreBone CEO Ohad Schwartz explained to ISRAEL21c. “They must be bioactive, not just a passive scaffold, in order to attract new bone cells; they must be strong enough to support the site, especially for implants; they must allow for being replaced as new bone grows; and they must be porous to enable vascularity,” meaning that blood vessels can grow through them naturally and produce growth of bone from the inside out.
“If you have all those features, you have a very good bone graft,” Schwartz continued. “We have all of those.”
Corebone has patented a new source for bone replacements using a material that has all these qualities – their own farm-grown coral.
The company grows its corals from selected species using patented technology to provide bioactivity and eliminate biological contamination. Different species are used for different applications. The corals are bred in a farm in the Arava desert near the Dead Sea, so they aren’t susceptible to marine pollution, contamination and or endangerment from human or marine activity. They also grow 10 times faster than in nature. They also avoid some of the difficulties with some organic grafts from animals or humans, the risk of rejection and transmission of disease.
Synthetic, man-made materials used in grafts don’t have these problems but are much weaker than natural bone. The global markets for orthopedic and dental bone-graft substitutes are expected to reach $3.4 billion and $1 billion respectively in 2017.